동물분자생체공학연구소 주관 초청강연 53
연사 : 임지영 교수 (국민대학교)
제목 : Effect of phospholipid matrix on physiological activities
일시 : 2023년 11월 16일 목요일 오후 2시
장소 : 생명과학관 서관 103호
초록
The effects of phospholipid (PL) matrices on phytosome formation, emulsion stability and in vitro simulated lipid digestion were investigated. Different phospholipid matrix resulted in significant difference in size, mechanical 25 property and solubility of chrysin-loaded phytosome (CP). CP displayed greater glucose promoting effect than free chrysin in muscle cells via stimulating gene expressions of peroxisome proliferator-activated receptor γ and glucose transporter type 4. CP treatment suppressed gluconeogenesis via down regulation of phosphoenolpyruvate carboxykinase while it promoted glucose uptake in the skeletal muscle and liver of db/db mice. Lipid digestibility in model infant formula emulsion was altered depending on the type of PL matrix, and SM displayed a superior effect to PC. Thus, the creation of a novel emulsion interface by the appropriate selection of emulsifiers can be used to improve lipid digestion in infants and obtain desirable nutritional consequences.